Advances in ADMET & Toxicology
(A100) A High-Throughput In Vitro ADME Assay Panel: Incorporation of SPE/MS/MS Into Standard Laboratory Workflow
Vaughn P. Millier -
 
     
   
  Advances in ADMET & Toxicology
(A110) A New Platform for Evaluation of Cytochrome P450 Induction
Jeff Johnson, PhD -
 
     
   
  Advances in ADMET & Toxicology
(A109) Automated Triplexed Hepatocyte-Based CYP1A, CYP3A And Viability Assays In 96 And 384-well Microplates
Brad Larson -
 
     
   
  Advances in ADMET & Toxicology
(A102) Automation of B-CLEAR® Technology for Evaluation of Drug Transport.
Cassandra H. Perry -
 
     
   
  Advances in ADMET & Toxicology
(A103) Electrophysiological Cardiac Safety Assessment in Drug Discovery and Development
Dirk Winkler -
 
     
   
  Advances in ADMET & Toxicology
(A108) Generation of New, Highly Restrictive. Conditionally Immortalized Human Brain Microvascular Endothelial Cell Line
Anatoliy Koval -
 
     
   
  Advances in Assay Technology
(B200) A High-Throughput 1,536-Well Luminescence Assay for Glutathione S-Transferase Activity
Adam Yasgar -
 
     
   
  Advances in Assay Technology
(B266) A Homogeneous Assay to Replace EMSA in the Monitoring of DNA-Protein Interaction.
Dahan Sophie -
 
     
   
  Advances in Assay Technology
(B205) A Method to Develop High Affinity Protein Ligands - Backwards
Chris Diehnelt -
 
     
   
  Advances in Assay Technology
(B206) A Multiplexed Screening Method Correlating Compound Toxicity Dose Effects with Cell Type, Cell Health and Culture Conditions Utilizing the HyperCyt® System for High-throughput Flow Cytometry.
Christopher Black -
 
     
   
  Advances in Assay Technology
(B207) A Novel Assay to Measure Renin Activity in Mouse Plasma
Elizabeth Cauchon -
 
     
   
  Advances in Assay Technology
(B208) A Novel Feeder-Free Pluripotent Stem Cell Culture Substrate that Supports Mouse Embryonic and Human Induced Pluripotent Stem Cell Growth and Proliferation
Thomas Zarembinski -
 
     
   
  Advances in Assay Technology
(B211) A Real-time Fluorescence Assay development for Specialized Human DNA Polymerases
Dorjbal Dorjsuren -
 
     
   
  Advances in Assay Technology
(B212) Adaptation of Angiogenesis and Cancer Cell Invasion Assays in to Well Plate Microfluidic Flow Devices Enables Using Real-Time Microscopy
Carolyn Conant -
 
     
   
  Advances in Assay Technology
(B213) Adhesive Micropatterns for High Content Screening: A Case Study
Constantin Nelep -
 
     
   
  Advances in Assay Technology
(B214) Aequorin Assays In Primary Endothelial Cells Using the Amaxa® Nucleofector® Technology
Ann Siehoff -
 
     
   
  Advances in Assay Technology
(B216) Analysis Of TrkB Activity In Complex With TDA 2.0™: A HTS-Compatible Assay with Altered Relevant Substrate Preference
Scott Gridley -
 
     
   
  Advances in Assay Technology
(B279) Assessing Mechanism of Action Of Cytotoxicity Using High Content Imaging Methods
Chandrasekaran Vasudevan -
 
     
   
  Advances in Assay Technology
(B257) Assessing Protein Structural Changes by Dual Polarization Interferometry
Kristin Coan -
 
     
   
  Advances in Assay Technology
(B220) Automated and Real-Time Monitoring Of Cell Migration, Cell Invasion and Cell Scattering Using The xCELLigence System from Roche Applied Science
Jing Zhang -
 
     
   
  Advances in Assay Technology
(B221) Bacterial Motility Assay in 384-Well Format for HTS
Lucile White -
 
     
   
  Advances in Assay Technology
(B222) Biomarker Analysis of GADD34 Induction by Proteasome Inhibition from Cell Culture & Xenograft Tumor Lysates Using the BioScale’s Acoustic Membrane and Microparticle (AMMP™) technology on the ViBE™ Bioanalyer
Michael Bembenek -
 
     
   
  Advances in Assay Technology
(B217) Catalytic Activity of Receptor Tyrosine Kinase Cytoplasmic Domains Strongly Dependant on Template-Directed Assembly
Scott Gridley -
 
     
   
  Advances in Assay Technology
(B224) Cell-Based Assays for G-Protein Independent Signaling Using Arrestin Binding and Endocytosis
DiscoveRx Corporation -
 
     
   
  Advances in Assay Technology
(B225) Characterization of Novel Beta-Subunit-Selective Luminogenic Substrates of the Proteasome
Khristofer Garcia -
 
     
   
  Advances in Assay Technology
(B227) Comparison of Microplate Surface Treatments for Use In Calcium Channel Assays
Mark Rothenberg -
 
     
   
  Advances in Assay Technology
(B280) Creating Cell-Based Assays for Screening GPCRs, Ion Channels and Other Targets in Cell Lines and Primary Cells Using the MaxCyte® STX™ Scalable Transient Transfection System
James Brady, PhD -
 
     
   
  Advances in Assay Technology
(B228) Cytotoxicity Profiling of the Anticancer Agent Thiostrepton
Paul held -
 
     
   
  Advances in Assay Technology
(B230) Development of a Live-Cell Based Reactive Oxygen Species (ROS) Assay for use in High-Content Screening of Drug Candidates Using the BioTek Synergy Mx Microplate Reader.
Xavier Amouretti -
 
     
   
  Advances in Assay Technology
(B231) Development of Label-Free Cell-Based Assays Using Primary Neuronal Cells
Alice Gao -
 
     
   
  Advances in Assay Technology
(B234) Evaluation of a Generic ADP Detection Assay: ADP-Glo™
Leng Lor -
 
     
   
  Advances in Assay Technology
(B235) Evaluation of Lewis Acid Kinase Assay Reagent and Comparison with IMAP
Hong Qian -
 
     
   
  Advances in Assay Technology
(B236) Expanding the Toolbox Of Gamma-Irradiated Frozen Cells Validated for GPCR-Mediated Kinase Signaling
Michael Crouch -
 
     
   
  Advances in Assay Technology
(B249) False Positives from a Homogeneous Time Resolved Fluorescence Screen Due to a Compound and Serum Interaction
David Cronk -
 
     
   
  Advances in Assay Technology
(B239) FLEXYTE Protease and Protein Kinase Assays: Realising the Benefits of Fluorescence Lifetime for Drug Discovery Applications
Graham Cotton -
 
     
   
  Advances in Assay Technology
(B281) Generating 1536-Well Assay Ready Plates On Demand for HTS Dose Response Curves Using Acoustic Technology
Manori Turmel -
 
     
   
  Advances in Assay Technology
(B240) Genetic Chemistry Platform Applied to Identification of Anti-Viral Compounds
Markus Schwab -
 
     
   
  Advances in Assay Technology
(B243) High Throughput Detection of Antibiotic Resistance Markers on Microarray Using Stringency Wash Optimized Workstation.
Olga Golovleva -
 
     
   
  Advances in Assay Technology
(B244) High Throughput Imaging Assays to Assess Cell Migration
Jayne Hesley -
 
     
   
  Advances in Assay Technology
(B246) Highly Sensitive Fluorimetric Assay for Thiol Quantification
Ming Zhu -
 
     
   
  Advances in Assay Technology
(B247) High-Throughput Multiplexed Assay For Analysis Of Hematopoietic Stem Cells Differentiation And Hematopoietic Toxicity
Oksana Sirenko -
 
     
   
  Advances in Assay Technology
(B2107) Homogeneous Cell-Based Signal Transduction Assays
Peter Banks -
 
     
   
  Advances in Assay Technology
(B237) HTS-Amenable Cell-Based Assays for Endogenous STAT1/3/5 Protein Phosphorylation for Drug Screening of Cytokine Pathways
Michael Crouch -
 
     
   
  Advances in Assay Technology
(B283) Identification of Protein Phosphatase-5 (PP5) Inhibitors by Fluorescence-Based Biochemical Ultra High Throughput Screening Assay
Claude-Henry Volmar, PhD -
 
     
   
  Advances in Assay Technology
(B284) Identification of Small Molecule Inhibitors of Platelet Granule Secretion; Development of Novel Label-Free High Throughput Assay
Joseph Negri -
 
     
   
  Advances in Assay Technology
(B285) Illuminating Insights From a Chemical Profile of Firefly Luciferase Inhibitors
Natasha Thorne -
 
     
   
  Advances in Assay Technology
(B286) In Search Of New Antifungal Agents: Ultra High Throughput Screening For TPT1 Inhibitors
Anna Knapinska -
 
     
   
  Advances in Assay Technology
(B287) Localised Surface Plasmon Resonance (LSPR) with Colloidal Gold Nanoparticles: A Novel Approach to High Throughput and Sensitive Label-Free Detection on Standard Laboratory Equipment
Patrick Englebienne -
 
     
   
  Advances in Assay Technology
(B289) Meganuclease-Driven Targeted Integration In CHO-K1 Cells for the Fast Generation of HTS Compatible Cell-Based Assays
Olivier Nosjean -
 
     
   
  Advances in Assay Technology
(B218) Mimicking Membrane-associated Kinase Activity in an in vitro Enzymatic Assay for HTS: Template-Directed Assembly of Lyn kinase using TDA 2.0™
Scott Gridley -
 
     
   
  Advances in Assay Technology
(B290) New Software Technology that Enables Scientists to Design and Build their own Assays
Carl Hull -
 
     
   
  Advances in Assay Technology
(B263) Novel Fluorescence-Based Microplate Assay for Screening Inhibitors of Thioredoxin and Protein Disulfide Isomerase
Andrew Whiteley -
 
     
   
  Advances in Assay Technology
(B2108) Optimizing A Luminescent Calcium Biosensor For Screening GPCRS On Multiple Detection Platforms
Blaine Armbruster -
 
     
   
  Advances in Assay Technology
(B291) Parallel Label-Free Fragment Screening Using A Biacore™ Prototype System
Olof Karlsson -
 
     
   
  Advances in Assay Technology
(B2104) Profiling Compound Toxicity Using Label-Free BIND® Technology from SRU Biosystems
Eric Sandberg -
 
     
   
  Advances in Assay Technology
(B265) Rapid Cell-based Assays using Multiplexed Mitochondrial and Cell Health Markers
Julie L. Clor -
 
     
   
  Advances in Assay Technology
(B209) Rapid Fragment Screening with a Robotically Automated ForteBio Octet RED384
Frank Podlaski -
 
     
   
  Advances in Assay Technology
(B293) Rapid, Cost Effective and Easy Screening of Membrane Proteins
Kenneth Olesen -
 
     
   
  Advances in Assay Technology
(B295) Screening Genetic Diversity Using Automated Highly Parallel Cell Culture
Robin Felder -
 
     
   
  Advances in Assay Technology
(B267) Secreted App and Amyloid Beta Quantification In SH-SY5Y Cell Media Using High Sensitivity Alphalisa Kits
Dahan Sophie -
 
     
   
  Advances in Assay Technology
(B269) Selective Cell Killing Using Photo-Acid-Generating Polymers
Kyoko Kikuchi -
 
     
   
  Advances in Assay Technology
(B271) Small Molecule and Fragment Screening using Bio-Layer Interferometry
Sriram Kumaraswamy -
 
     
   
  Advances in Assay Technology
(B272) SWAP: A High Throughput Automated Microfluidic Alternative to Western Blotting
Laurel Provencher, PhD -
 
     
   
  Advances in Assay Technology
(B273) Transcreener® Assay ADP2 Assays: Streamlining Inhibitor Profiling for Kinases with Diverse ATP Requirements
Meera Kumar -
 
     
   
  Advances in Assay Technology
(B274) TR-FRET HTS Statistical Method for Outlier Identification
Patrick Bingham -
 
     
   
  Advances in Assay Technology
(B275) Two Secreted Orthogonal Bioluminescent Reporters for Ultrasensitive High Throughput Assays
George Tzertzinis -
 
     
   
  Advances in Assay Technology
(B298) Ultra-High-Throughput Screening of Poorly Characterized Enzymes via Fluorescence Polarization- Activity-Based Protein Profiling (fluopol-ABPP)
Virneliz Fernandez-Vega -
 
     
   
  Advances in Assay Technology
(B276) Up- And Down-Regulation Caused By RXR Agonist And HMG-CoA Reductase Inhibitor are Detectable With HTRF® Apo-A1 And Apo-B Assays.
Koji Adachi -
 
     
   
  Advances in Assay Technology
(B277) Using Polypropylene Microplates in Luminescence Based Biochemical Assays
Rainer Heller -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C301) A Mix-and-Read Cell-Based Assay for Antibody Screening Against Epithelial Growth Factor Receptor
Donald Bennett -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C303) An Automated, High Throughput Screening System to Perform Large Scale Screening of Cellular Assays
Patrick Humphrey -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C306) Automated High-Throughput Single-Cell Cytotoxicity Analysis By Flow Cytometry - Integrated Biomek® -HyperCyt®-CyAn ADP Workstation"
Michael Kowalski -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C307) Automated Nanolitre Hit-Picking Using A Mosquito® X1 Low Volume Pipettor
Joby Jenkins -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C319) Evaluating Five Microplate Mixing Techniques  Diffusion, Centrifugation, Shaking, Pipetting and Ultrasonic Mixing
Jean Shieh -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C313) Evaluation of the Formulatrix Tempest at Emd Serono: A Flexible Low Volume Liquid Handler with Two Axis Gradient Dispensing Capability.
Vikram Shankar -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C337) Exploring the Benefits of Echo Dispensing into Cell Plates
Stacey Barto -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C314) Gradient, Contact-Free, Volume Transfers Minimize Compound Loss in Dose-Response Experiments
Joe Olechno -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C315) High Throughput Acoustic Cherry Picking and Dose Response Applications on a Highly Flexible Automation Platform
Jack Dawson -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C317) High-Precision Acoustic Transfer of Buffered Solutions Containing Surfactant and Protein for Miniaturized Biological Assays
Sammy S. Datwani -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C316) HighRes Biosolutions NanoCell: A Novel Robotic Platform for Multiple Use Laboratories
Jack Dawson -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C312) Implementing Digital Video Recording to Increase Laboratory Efficiency
Simon Rose -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C320) Improve the Integrity of Your Fragment Library for Fragment-Based Drug Discovery
Jean Shieh -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C336) Improving Screening Results Using High-Speed Vision Technology
Chris Walsh -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C322) Integration of Acoustic Liquid Transfer Technology into a Cellular Profiling Workflow
Timothy Smith -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C323) Label Free Technology: The Weird and Wonderful World of Cell Signalling
David Cronk -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C324) Label Free Technology: Value Added Information in the Drug Discovery Process
David Cronk -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C327) New Driver Design Increases Throughput of FLIPR TETRA System Intergrated On BioCel Robot
Avian E. Townley -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C329) Optimization of the Protocol For DNA Purification From Blood for Thermo Scientific Kingfisher Flex
Merja Mehto -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C330) Precise and Accurate Transfer of Kinase Enzymes Using Acoustic Droplet Ejection
howard lee -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C331) Rapid Generation of Assay-Ready Serial Dilution Plates Using Two Stage Low Volume Pipetting
Ben Schenker -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C332) Rapid N-Glycan Analysis Sample Prep on an Automatable Micro Chromatography Platform
Scott Fulton -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C335) Uncovering Liquid Handler Behavior - Do you Really Know How your Robot is Performing for Your Assays?
John Bradshaw -
 
     
   
  Advances in Automation, Liquid Handling and Detection Platforms
(C321) Utilizing an Automated Tissue Culture Platform to Characterize, Maintain, Expand and Screen Adherent and Suspension Cell Lines
Timothy Smith -
 
     
   
  Advances in High Content Screening and Information Technologies
(D400) A New Microconduit Array Plate for Neutrophil Chemotaxis That is Compatible with High Throughput Laser Scanning Instrumentation
Tracy Worzella -
 
     
   
  Advances in High Content Screening and Information Technologies
(D401) A Nine-Parameter Cytotoxicity Assay to Determine the Toxic Effects of Compounds In HepG2 Cells
Yang Tian -
 
     
   
  Advances in High Content Screening and Information Technologies
(D402) A Novel Genome-wide Screening Application Using Pooled Viral miRNA-adapted shRNA (shRNAmir) Libraries
Kruti Patel -
 
     
   
  Advances in High Content Screening and Information Technologies
(D415) A Novel Method to Simultaneously Quantify Antibody Production and Cell Health Utilizing the System for Cell-based Screening.
Thomas Duensing -
 
     
   
  Advances in High Content Screening and Information Technologies
(D416) Autoantigen Biomarker Discovery Through Immunological Profiling with Functional Protein Microarrays
Thien Dinh -
 
     
   
  Advances in High Content Screening and Information Technologies
(D404) Automation Of Complex Cell Models - Investigating Modulators of Angiogenesis In Vitro
Anesh Sitaram -
 
     
   
  Advances in High Content Screening and Information Technologies
(D405) BacMam Gene Expression In Neurons For Functional And Imaging Applications
Daniel Beacham -
 
     
   
  Advances in High Content Screening and Information Technologies
(D406) Development of a Fluorescence-Based Assay to Screen Drugs Against AlzheimerS Disease
Clarisa Salado -
 
     
   
  Advances in High Content Screening and Information Technologies
(D408) High Throughput TCRP-based Phenotypic Screening for Anticancer Drug Discovery Using the xCELLigence Label-free Cell-Based Assay System
Min Zheng -
 
     
   
  Advances in High Content Screening and Information Technologies
(D409) High-Throughput Analysis of Nuclear Dynamics through the Combination of a Novel Cell-Permeant Fluorescent Probe and a Laser-Scanning Microplate Cytometer
Paul Wylie -
 
     
   
  Advances in High Content Screening and Information Technologies
(D410) HyperCyt® PRO: An Advanced Platform for Collecting, Managing and Sharing Data from Multiplate Flow Cytometry Screening
Linda S. Trinkle -
 
     
   
  Advances in High Content Screening and Information Technologies
(D412) Measuring of Migration in Fully Automated Imaging Based Approach
Simone Schicktanz -
 
     
   
  Advances in High Content Screening and Information Technologies
(D413) Simultaneous Measurement of Cytotoxicity, Proliferation and Cell Cycle Progression using a Simple Two Dye Method
Wayne Bowen -
 
     
   
  Advances in High Content Screening and Information Technologies
(D414) Use of Muscale CMAcfz Automated Image Analysis Software to Accurately Quantitate Cell Migration
Asaad Said -
 
     
   
  Critical Reagents: Library Design, Sample Management, Biologicals and Logistics
(E508) Are Natural Products Delivering? Experiences and Recommendations From 20 Screening Campaigns.
Peter Eckard -
 
     
   
  Critical Reagents: Library Design, Sample Management, Biologicals and Logistics
(E500) BacMam Wave Bioreactor Process Optimization
Mark Tibbetts -
 
     
   
  Critical Reagents: Library Design, Sample Management, Biologicals and Logistics
(E501) Biological Properties of a Novel Stereochemically Diverse Compound Collection at the Broad Institute
Joshua Bittker -
 
     
   
  Critical Reagents: Library Design, Sample Management, Biologicals and Logistics
(E509) Cell-based Assays Using Biosensors and Reporter Genes in Primary Cells
Nicole Faust -
 
     
   
  Critical Reagents: Library Design, Sample Management, Biologicals and Logistics
(E502) Comparison of Mouse ES Cell-Derived Cardiomyocytes and Human iPS-Derived Cardiomyocytes for Electrophysiology: Use of Microelectrode Arrays
Silke Schwengberg -
 
     
   
  Critical Reagents: Library Design, Sample Management, Biologicals and Logistics
(E510) comPOUND D2: a simple approach to increasing sample storage capacity
Ben Schenker -
 
     
   
  Critical Reagents: Library Design, Sample Management, Biologicals and Logistics
(E505) High Quality Gene Assembly from Microarray Synthesized Oligonucleotides.
Alex Borovkov -
 
     
   
  Critical Reagents: Library Design, Sample Management, Biologicals and Logistics
(E512) Identification of Allosteric Agonists of CXCR4 Using a Pepducin Library
Yong Ren -
 
     
   
  Critical Reagents: Library Design, Sample Management, Biologicals and Logistics
(E506) Production of Multimeric Proteins With Two Different Techniques.
Lukas Leder -
 
     
   
  Critical Reagents: Library Design, Sample Management, Biologicals and Logistics
(E503) Susceptibility of Mouse ESC Derived Cardiomyocytes to Mitochondrial Toxicants in Cell Culture Media Using Different Sugars as Energy Source
Silke Schwengberg -
 
     
   
  Epigenetics Targets in Drug Discovery
(F601) A Homogeneous, Single Addition Bioluminescent Assay for Sirtuin Activities
Terry Riss -
 
     
   
  Epigenetics Targets in Drug Discovery
(F602) A Novel Non-Rad Homogeneous Assay Using the Alpha Technology to Monitor Full Length Histone Protein Methylation.
Nathalie Rouleau -
 
     
   
  Epigenetics Targets in Drug Discovery
(F604) Epigenetics Targets - Efficient Hit Finding Approaches
Doris Hafenbradl -
 
     
   
  Epigenetics Targets in Drug Discovery
(F605) HDAC2 Screening Assay Using the Fluor de Lys®-Green Substrate
Mark Engleka -
 
     
   
  GPCRs in Drug Discovery
(G729) A High Throughput Screen Using A Modified Camp Biosensor Assay to Identify Potential Gpcr Positive Allosteric Modulators
Victoria Wong -
 
     
   
  GPCRs in Drug Discovery
(G700) A PathHunterTM Ultra High Throughput Screen of a Gi-coupled GPCR Identifies Both Neutral and Beta-Arrestin-Biased Ligands
Amita Patel -
 
     
   
  GPCRs in Drug Discovery
(G701) A Wide Range of Compound Efficacies Revealed Using Pathhunter™ Arrestin Assays
DiscoveRx Corporation -
 
     
   
  GPCRs in Drug Discovery
(G705) Automated 1,536-Well Camp Assay for the Characterization of Agonists and Antagonists of A Gi-Coupled Receptor Using the New LANCE Ultra CAMP Kit
Lucille Beaudet -
 
     
   
  GPCRs in Drug Discovery
(G727) Automation of a Microplate Cell-based Assay to Measure Activity of the Histamine H1 G-protein-coupled receptor using GEM, a 3-D Cell Culture Matrix
Nadia Badr -
 
     
   
  GPCRs in Drug Discovery
(G715) Capturing Higher-Value GPCR Screening Data with a Combined Approach: The FLIPRTETRA® System and the Cellkey® System
Debra Gallant -
 
     
   
  GPCRs in Drug Discovery
(G724) Comparison Between The Path Hunter® Assay And The Flipr Tetra® System Cell-Based Assays For The Identification Of Human Oxytocin Receptor Agonists
William Janzen -
 
     
   
  GPCRs in Drug Discovery
(G720) Development of a Generic Sensor of GPCR Activation Using a Phospho-ERK2 Cellular Assay
Bonnie Hanson -
 
     
   
  GPCRs in Drug Discovery
(G709) Functional Profiling of Allosteric Modulators for Metabotropic Glutamate Receptors
Michel Detheux -
 
     
   
  GPCRs in Drug Discovery
(G725) Give Your GPCR a Second Chance
Stephan Schann -
 
     
   
  GPCRs in Drug Discovery
(G702) HitHunter ™cAMP and cAMP Hunter™HitHunter ™cAMP and cAMP Hunter™ Cell Lines: Your Solution for Use with High Serum Samples, Difficult Gi Targets and Identification of Allosteric Modulators Cell Lines: Your Solution for Use with High Serum Samples, Difficult Gi Targets and Identification of Allosteric Modulators
DiscoveRx Corporation -
 
     
   
  GPCRs in Drug Discovery
(G711) Identification of Novel Selective CB2 Agonists for Pain Treatment through an HTA Campaign with ChAMPion Technology
Daniele Carettoni -
 
     
   
  GPCRs in Drug Discovery
(G712) Identifying Positive Allosteric Modulators of a G-Protein Coupled Receptor Using A 2.0 uL Functional Cell Based Assay
Jeffrey Heath -
 
     
   
  GPCRs in Drug Discovery
(G713) Imaging System Enhancements to Enable Insightful High Content Analysis Investigations.
Hayley A. Tinkler -
 
     
   
  GPCRs in Drug Discovery
(G714) Label-Free Signaling Analysis of Fresh and Frozen Recombinant GPCR Cells Using The Corning EPIC® System
Janet Park -
 
     
   
  GPCRs in Drug Discovery
(G706) Lance Ultra Camp: A New, Two-Component Tr-Fret Camp Assay for HTS Of Gs- and Gi-Coupled Receptors
Lucille Beaudet -
 
     
   
  GPCRs in Drug Discovery
(G716) MC4R: Another Shot on Goal via Positive Allosteric Modulation
Lawrence Wolfe -
 
     
   
  GPCRs in Drug Discovery
(G717) Natural Ligand Identification of Orphan Receptors Using Tissue Extract Screening
Michel Detheux -
 
     
   
  GPCRs in Drug Discovery
(G703) PathHunter™ ß-Arrestin Assays: Determination of Pharmacology Differences between Human and Ortholog GPCRs
DiscoveRx Corporation -
 
     
   
  GPCRs in Drug Discovery
(G722) Quencher Dyes can Alter The Pharmacokinetic Response Profiles of Living Cells in Fluorescence-Based Calcium Mobilization Assays
Wayne Patton -
 
     
   
  GPCRs in Drug Discovery
(G723) Real-Time and High Throughput Measurement of cAMP in Live Cells Using Quest Fluo-8 Calcium Indicator
Jack Diwu -
 
     
   
  GPCRs in Drug Discovery
(G704) Unique Properties of PathHunter™ ß-Arrestin Assays for GPCR Antagonist Discovery and Characterizationn
DiscoveRx Corporation -
 
     
   
  GPCRs in Drug Discovery
(G718) Use of Multiplexing in the Evaluation of Prokineticin Receptor Ligands
Lisa Saville -
 
     
   
  GPCRs in Drug Discovery
(G726) Validation of ßarrestin Technology for the Identification of Inverse Agonists at the Cannabinoid 1 Receptor
Lucy M. Rogers -
 
     
   
  Ion Channels and Transporters in Drug Discovery
(H800) A Fast and Simple Method For Measuring P-Glycoprotein (Ppg) Inhibition - The Fluorosome®-Trans-Pgp Assay and the Fluostar Omega
EJ Dell -
 
     
   
  Ion Channels and Transporters in Drug Discovery
(H802) Characterization Of TRPV1 Channel Over-Expressed In Breast Cancer Cell Line Using Flipr Calcium And MTS Cell Viability Assays
Tina Wu -
 
     
   
  Ion Channels and Transporters in Drug Discovery
(H803) Generation of a High Throughput GABAA Receptor Assay to Detect Benzodiazepines
Cathryn Adams -
 
     
   
  Ion Channels and Transporters in Drug Discovery
(H804) High-Throughput Luminescence-Based Assay For Identifying CRAC Channel Inhibitors As Novel Therapeutic Agents For Immune Disease Treatment
Sabrina Corazza -
 
     
   
  Ion Channels and Transporters in Drug Discovery
(H808) Parallel Pharmacological Characterization Of Multiple Ion Channels Involved In Cardiac Risk Assessment Using Qpatch HTX.
Hervør Lykke Olsen -
 
     
   
  Ion Channels and Transporters in Drug Discovery
(H809) Screening of Drug Candidates against Malaria using a Novel Surface Plasmon Resonance (SPR) based Method
Magnus Brändén -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I902) A Homogeneous Fluorimetric HDAC Activity Assay Using Non-Peptide HDAC Green Substrate
Jack Diwu -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I903) Activity-Based Kinase Selectivity Profiling of Clinically Relevant Tyrosine Kinase Inhibitors Using Quickscout™
Masaki Gouda, Ph. D. -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I904) ADP Detection in FP, TR-FRET and FI Assay Formats: Versatile Kinase/ATPase Detection without the Use of Coupling Enzymes
Karen Kleman-Leyer, PhD -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I905) ADP Quest™ and ADP Quest™ HS: Universal ADP Accumulation Assay for Enzyme Kinetics
DiscoveRx Corporation -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I923) Biochemical Characterization of a Small Molecule Glycogen Synthase Activator
Qing Xiang -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I907) Comparison Of Binding And Activity Kinase Assays To Identify And Validate Fragment Hits For FBDD
Gary Asmussen -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I908) Competitive TR-FRET Binding Assays for PI3K Family Inhibitors
William J. Frazee -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I909) Convenient Kit for Assay of DPPIV/CD26 Activity in Biological Fluids
Diana L. Hulboy, PhD -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I910) Determination of Drug-Kinase Residence Time in a Homogenous, Low-Volume Format
Pete Conway -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I911) Development Of A High-Throughput Screen For Natural Product Inhibitors Of Human Tyrosyl-DNA-Phosphodiesterase (Tdp1)
Alun Bermingham -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I913) Evaluation of Lanthascreen™ Eu Kinase Binding Assay And Comparison to Three Mechanistically Distinct Kinase Assays for ITK
Mohammed Kashem -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I916) HotSpot(SM): A Novel Methyltransferase Assay Platform for Drug Screening and Discovery
Haiching Ma -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I918) Identification of Potent and Selective Cdc2-Like (Clk) Kinase Inhibitors Via an Orthogonal Assay Approach
Cordelle Tanega -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I919) Kinase Inhibitor Selectivity Profiling Utilizing a Versatile Tr-Fret Kinase Binding Assay Platform
Elizabeth J. Miller -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I920) Optimizing the Cost-Effectiveness of Large-Scale Kinase Profiling
Dongyu Sun -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I921) P38Alpha: A Fragment-Based Drug Discovery Case Study At Biofocus
David Cronk -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I906) PathHunter™ Cell-Based Kinase Assays: A Portfolio of HTS-friendly Cytoplasmic or Receptor Tyrosine Kinase Assays for Small Molecule Inhibitors as well as Monoclonal Antibodies
DiscoveRx Corporation -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I927) Phosphatase Assays Using the LANCE Ultra Technology
Lucille Beaudet -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I924) Profiling Kinase Activities Using A Universal Luminescent ADP Detection Platform
Hicham Zegzouti -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I929) Simultaneous Monitoring of Phosphorylation Events and Protein-Protein Interactions in the ERK MAP Kinase Pathway
Mathieu Arcand -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I928) Target Immobilization as a Strategy for NMR Based Fragment Screening: Comparison of TINS, 1D-STD and SPR for Fragment Hit Identification
Robert J. Heetebrij -
 
     
   
  Kinases and Other Enzymes in Drug Discovery
(I925) The Transcreener® ADP2 Universal Kinase Assay from BellBrook Labs is Readily Performed on Two BMG LABTECH Microplate Readers Using Different Assay Formats
EJ Dell -
 
     
   
  Lead Discovery in Immunoinflammation
(J1000) A Microconduit Array Plate Designed for High Content Leukocyte Chemotaxis Assays in the Presence of a Stable Gradient
Tracy Worzella -
 
     
   
  Lead Discovery in Immunoinflammation
(J1009) Flavocoxid, a Natural, Novel Flavonoid-Based Anti-inflammatory with a Broad Mechanism of Action Providing Safer and Effective Inflammatory Management of Disease
Bruce Burnett -
 
     
   
  Lead Discovery in Immunoinflammation
(J1003) High-Throughput Multiplexed Inflammation Assay Using Primary Cells
Evan F. Cromwell -
 
     
   
  Lead Discovery in Immunoinflammation
(J1004) Identification and Characterisation of Novel Dual TBK1/IKKe Inhibitors
Ahmad Kamal -
 
     
   
  Lead Discovery in Neurosciences
(K1104) A High Throughput Kinetics Imaging Detector for Measuring Intracellular Calcium Increase Through Cold Activation Of Ion Channels
Judy Wang -
 
     
   
  Lead Discovery in Neurosciences
(K1101) Demonstration of constitute activity of the class B orphan GPCR (LPHN1), using beta- Lactamase reporter system.
Victoria Yatsula -
 
     
   
  Lead Discovery in Neurosciences
(K1108) High-Throughput Screening in Embryonic Stem Cell-derived Neurons to Identify Potentiators of AMPA-type Glutamate Receptors
Laura Zawadzke -
 
     
   
  Lead Discovery in Neurosciences
(K1102) Identification of Potent and Selective Inhibitors of LRRK2
Alison Levy -
 
     
   
  Lead Discovery in Neurosciences
(K1106) Multidimensional Investigation Of Cell Surface Receptors Using The Tag-Lite™ Technology
Thomas Roux -
 
     
   
  Lead Discovery in Neurosciences
(K1107) Novel Platform for Highly Parallel Patch Clamp Recordings - A Revolution In Ion Channel Screening
Rodolfo J. Haedo -
 
     
   
  Lead Discovery in Neurosciences
(K1103) Strategy for the Identification and Development of Novel JNK3 Inhibitors as Therapeutics for Huntingtons Disease
Macarena Irigoyen -
 
     
   
  Lead Discovery in Oncology Research
(L1200) An Automated High-Content Assay for Tumor Cell Migration Through 3-Dimensional Matrices
Steven Hayes -
 
     
   
  Lead Discovery in Oncology Research
(L1203) Evaluation of Nuclear Hormone Receptor Cell Assay Approaches - Comparison of the Discoverx Pathhuntertm Format Versus Reporter nd Endogenous End-Points.
Graeme E. Walker -
 
     
   
  Lead Discovery in Oncology Research
(L1204) High Content Analysis (HCA) Approaches in Development of Differentially Conditioned Human Melanoma Cell Lines as Tools for Screening and Characterization of Therapeutic Drug Candidates
Elizabeth Roquemore, PhD -
 
     
   
  Lead Discovery in Oncology Research
(L1205) High-Content Screen for Inhibitors of Cell Migration in Cancer Metastasis Using Adenoviral Knock-Down
Nathalie Joly -
 
     
   
  Lead Discovery in Oncology Research
(L1211) Impedance Based Kinetic Monitoring of Cellular Response In Drug Discovery and Development
Ning Ke -
 
     
   
  Lead Discovery in Oncology Research
(L1215) Mode of Action Analysis of Sorafenib by Integrating Chemical Proteomics and Phosphoproteomics
Jutta Fritz -
 
     
   
  Lead Discovery in Oncology Research
(L1206) Natural Products Targeting Oncology Pathways
Peter Eckard -
 
     
   
  Lead Discovery in Oncology Research
(L1212) Poly(ADP Ribose)Polymerases: Profiling of Inhibitor Selectivity dor Parp-Family Members Using Biacore™ Technology
Johan Weigelt -
 
     
   
  Lead Discovery in Oncology Research
(L1207) Utilizing Primary Cell-Based Screening with the Exvitech© Platform to Identify Novel Uses for Existing Drugs
Teresa Bennett -
 
     
   
  Other Targets in Drug Discovery
(M1309) A High Throughput Screen For Phop Regulon Inhibitors in Salmonella Typhi
LaKeisha Woods -
 
     
   
  Other Targets in Drug Discovery
(M1300) A Novel Fluorimetric Assay for the Detection of Separase Enzyme Activity
Xiaohe Tong -
 
     
   
  Other Targets in Drug Discovery
(M1312) CCR5-Tropic HIV-1 Fusion Inhibition Assay for HTS
Kanupriya Whig -
 
     
   
  Other Targets in Drug Discovery
(M1315) Functional, Cell-Based Pathway Assays Using Pathhunter™Technology
DiscoveRx Corporation -
 
     
   
  Other Targets in Drug Discovery
(M1304) High Throughput DNA Analysis and Quantization Using Microliter Scale Sample Volumes
Hanna Grano -
 
     
   
  Other Targets in Drug Discovery
(M1317) High Throughput Screen Assays for Identifying Inhibitors of Protein-RNA Binding as a Potential Treatment for Myotonic Dystrophy Type-1
Catherine Chen -
 
     
   
  Other Targets in Drug Discovery
(M1306) Kinaffinityâ Facilitates Effective and Reliable Profiling of Kinase Inhibitors In Cells and Tissue
Jutta Fritz -
 
     
   
  Other Targets in Drug Discovery
(M1319) Novel Screening Assay and Development of Potent Inhibitors of H-PGDS
Jeff Johnson, PhD -
 
     
   
  Other Targets in Drug Discovery
(M1321) The Influence of Data Content in Deriving Polypharmacology Relationships
Emily Nicholl -
 
     
   
  Other Targets in Drug Discovery
(001) Utilizing a Standard Language in an EHR to Collect Data for Quality Programs, Research, and Reporting
Carol A. Petersen, RN, BSN, MAOM, CNOR -
 
     

 

 
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